... of parasympathetic activity. e Probably M 1 , but M 2 may participate in some locations. ACh, acetylcholine; NE, norepinephrine. Modified with permission from Katzung BG, Vanderah TW: Basic & Clinical Pharmacology, 15th ed. New York, NY: McGraw Hill; 2021. Mydriasis can be caused...

...Basic & Clinical Pharmacology (Katzung and Trevor) McGraw-Hill Professional, http://www.mcgraw-hill.com . This text, organized by therapeutic class of agents, provides general discussion of pharmacology principles as well as more detailed discussion of specific agents. Figures and tables...

... (ecstasy); SSRIs, selective serotonin reuptake inhibitors. Reproduced with permission from Katzung BG, Vanderah TW: Basic & Clinical Pharmacology, 15th ed. New York, NY: McGraw Hill; 2021. A 40-year-old man with obesity (BMI 33) is to be treated with semaglutide. Which of the following...

...BASIC & CLINICAL PHARMACOLOGY OF THE GANGLION-BLOCKING DRUGS Ganglion-blocking agents competitively block the action of acetylcholine and similar agonists at neuronal nicotinic receptors of both parasympathetic and sympathetic autonomic ganglia. Some members of the group also block the ion...

...Basic Pharmacology & Clinical Uses After ingestion, bithionol reaches peak blood levels in 4–8 hours. Excretion appears to be mainly via the kidney. For treatment of paragonimiasis and fascioliasis, the dosage of bithionol is 30–50 mg/kg in two or three divided doses, given orally after...

...BASIC & CLINICAL PHARMACOLOGY OF DRUGS USED IN HYPERLIPIDEMIA The decision to use drug therapy for hyperlipidemia is based on the specific metabolic defect and its potential for causing atherosclerosis or pancreatitis. Suggested regimens for the principal lipoprotein disorders are presented...

... insulin increases considerably when dosage is increased due to increased hexamer formation. (Reproduced with permission from Katzung BG, Vanderah TW: Basic & Clinical Pharmacology, 15th ed. New York, NY: McGraw Hill; 2021.) Because of the risk of brain damage, the most important complication...

...) is the anesthetic concentration that eliminates the response in 50% of patients exposed to a standardized painful stimulus. In this table, MAC is expressed as a percentage of the inspired gas mixture. Modified with permission from Katzung BG, Vanderah TW: Basic & Clinical Pharmacology, 15th ed. New York...

...BASIC PHARMACOLOGY OF AGENTS USED IN THE TREATMENT OF ASTHMA The drugs most used for asthma management are adrenoceptor agonists or sympathomimetic agents (used as “relievers” or bronchodilators) and inhaled corticosteroids (used as “controllers” or anti-inflammatory agents). Their basic...

...BASIC PHARMACOLOGY OF THE DIRECT-ACTING CHOLINOCEPTOR STIMULANTS The direct-acting cholinomimetic drugs can be divided on the basis of chemical structure into esters of choline (including acetylcholine) and alkaloids (such as muscarine and nicotine). Many of these drugs have effects on both...