This Appendix contains tables of reference values for common laboratory tests. A variety of factors can influence reference values. Such variables include the population studied, the duration and means of specimen transport, laboratory methods and instrumentation, and even the type of container used for the collection of the specimen. The reference or “normal” ranges given in this appendix may therefore not be appropriate for all laboratories, and these values should only be used as general guidelines. Whenever possible, reference values provided by the laboratory performing the testing should be used in the interpretation of laboratory data. Values supplied in this Appendix reflect typical reference ranges in nonpregnant adults. Pediatric reference ranges and values in pregnant patients may vary significantly from the data presented in the Appendix.
In preparing the Appendix, the authors have taken into account the fact that the system of international units (SI, système international d’unités) is used in most countries and in some medical journals. However, clinical laboratories may continue to report values in “traditional” or conventional units. Therefore, both systems are provided in the Appendix. The dual system is also used in the text except for those instances in which the numbers remain the same and only the terminology is changed (mmol/L for meq/L or IU/L for mIU/mL), when only the SI units are given.
TABLE 1Hematology and Coagulation |Favorite Table|Download (.pdf) TABLE 1 Hematology and Coagulation
|Analyte ||Specimen ||SI Units ||Conventional Units |
|Activated clotting time ||WB ||70–180 s ||70–180 s |
|Activated protein C resistance (factor V Leiden) ||P ||Not applicable ||Ratio >2.1 |
|ADAMTS13 activity ||P ||≥0.67 ||≥67% |
|ADAMTS13 inhibitor activity ||P ||Not applicable ||≤0.4 U |
|ADAMTS13 antibody ||P ||Not applicable ||≤18 U |
|Alpha2 antiplasmin ||P ||0.87–1.55 ||87–155% |
|Antiphospholipid antibody panel || || || |
| PTT-LA (lupus anticoagulant screen) ||P ||Negative ||Negative |
| Platelet neutralization procedure ||P ||Negative ||Negative |
| Dilute viper venom screen ||P ||Negative ||Negative |
|Anticardiolipin antibody ||S || || |
| IgG || ||0–15 arbitrary units ||0–15 GPL |
| IgM || ||0–15 arbitrary units ||0–15 MPL |
|Beta-2 glycoprotein 1 antibodies ||S || || |
| IgG || ||0–20 arbitrary units ||0–20 SGU |
| IgM || ||0–20 arbitrary units ||0–20 SMU |
|Antithrombin III ||P || || |
| Antigenic || ||220–390 mg/L ||22–39 mg/dL |
| Functional || ||0.7–1.30 U/L ||70–130 % |
|Anti-Xa assay (heparin assay) ||P || || |
| Unfractionated heparin || ||0.3–0.7 kIU/L ||0.3–0.7 IU/mL |
| Low-molecular-weight heparin || ||0.5–1.0 kIU/L ||0.5–1.0 IU/mL |
| Danaparoid (Orgaran) || ||0.5–0.8 kIU/L ||0.5–0.8 IU/mL |
|Autohemolysis test ||WB ||0.004–0.045 ||0.4–4.50% |
|Autohemolysis test with glucose ||WB ||0.003–0.007 ||0.3–0.7% |
|Bleeding time (adult) || ||<7.1 min ||<7.1 min |
|C4 binding protein ||P ||305–695 mg/L ||30.5–69.5 mg/dL |
| ||S ||275–604 mg/L ||27.5–60.4 mg/dL |
|Clot retraction ||WB ||0.50–1.00/2 h ||50–100%/2 h |
|Cryofibrinogen ||P ||Negative ||Negative |
|D-dimer ||P ||220–740 ng/mL FEU ||220–740 ng/mL FEU |
|Differential blood count ||WB || || |
|Relative counts: || || || |
| Neutrophils || ||0.40–0.70 ||40–70% |
| Bands || ||0.0–0.05 ||0–5% |
| Lymphocytes || ||0.20–0.50 ||20–50% |
| Monocytes || ||0.04–0.08 ||4–8% |
| Eosinophils || ||0.0–0.6 ||0–6% |
| Basophils || ||0.0–0.02 ||0–2% |
|Absolute counts: || || || |
| Neutrophils || ||1.42–6.34 × 109/L ||1420–6340/mm3 |
| Bands || ||0–0.45 × 109/L ||0–450/mm3 |
| Lymphocytes || ||0.71–4.53 × 109/L ||710–4530/mm3 |
| Monocytes || ||0.14–0.72 × 109/L...|
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