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INTRODUCTION

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Oxcarbazepine is an iminostilbene derivative related to the tricyclic antidepressants that is used in the treatment of tonic-clonic (grand mal), partial, or secondarily generalized seizures (Table 17-1).1,2,3, and 4 Lack of an intravenous dosage form has limited its use in the treatment of acute seizures. Thus, the drug is used primarily as a prophylactic agent in the chronic therapy of epilepsy. Oxcarbazepine is also a useful agent to treat bipolar affective disorders and neurogenic pain (trigeminal neuralgia, diabetic neuropathy, etc) after carbamazepine has been considered.5,6,7, and 8

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TABLE 17-1International Classification of Epileptic Seizures With Recommended Therapies

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