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Medications Tha..
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Human liver P450s (CYPs), and some of the drugs metabolized (substrates) inducers, and selective inhibitors. Note: Some P450 substrates can be potent competitive inhibitors and/or mechanism-based inactivators.

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CYP Substrates Inducers Inhibitors
1A2 Acetaminophen, antipyrine, caffeine, clomipramine, duloxetine, melatonin, phenacetin, ramelteon, tacrine, tamoxifen, theophylline, warfarin Smoking, charcoal-broiled foods, cruciferous vegetables, lansoprazole, omeprazole Galangin, furafylline, fluvoxamine
2A6 Coumarin, tobacco nitrosamines, nicotine (to cotinine and 2′--hydroxynicotine) Efavirenz, rifampin, phenobarbital Tranylcypromine, menthofuran, methoxsalen
2B6 Artemisinin, bupropion, clopidogrel, cyclophosphamide, efavirenz, ifosfamide, ketamine, S-mephobarbital, S-mephenytoin (N-demethylation to nirvanol), methadone, nevirapine, propofol, selegiline, sertraline, ticlopidine Phenobarbital, cyclophosphamide Clopidogrel, paroxetine, phencyclidine, sertraline, thiotepa, ticlopidine
2C8 Taxol, all-trans-retinoic acid Rifampin, barbiturates Gemfibrozil, montelukast, trimethoprim, quercetin, rosiglitazone, pioglitazone
2C9 Celecoxib, diclofenac, flurbiprofen, hexobarbital, ibuprofen, losartan, phenytoin, tolbutamide, trimethadione, sulfaphenazole, S-warfarin, ticrynafen Barbiturates, carbamazepine, rifampin Fluconazole, fluvoxamine, sulfaphenazole, tienilic acid
2C18 Tolbutamide, phenytoin Phenobarbital
2C19 Diazepam, S-mephenytoin, naproxen, nirvanol, omeprazole, propranolol Barbiturates, rifampin N3-benzylnirvanol, N3-benzylphenobarbital, fluconazole, nootkatone, ticlopidine
2D6 Atomoxetine, bufuralol, bupranolol, clomipramine, clozapine, codeine, debrisoquine, desipramine, dextromethorphan, encainide, flecainide, fluoxetine, guanoxan, haloperidol, hydrocodone, 4 --methoxy-amphetamine, metoprolol, mexiletine, nebivolol, oxycodone, perphenazine, paroxetine, phenformin, propafenone, propoxyphene, risperidone, selegiline (deprenyl), sparteine, tamoxifen, tolterodine, thioridazine, timolol, tricyclic antidepressants, venlafaxine Unknown Bupropion, fluoxetine, paroxetine, quinidine
2E1 Acetaminophen, chlorzoxazone, enflurane, halothane, ethanol (a minor pathway) Ethanol, isoniazid Clomethiazole, disulfiram, diethyldithiocarbamate, diallyl sulfide, 4 --methylpyrazole
3A41 Acetaminophen, alfentanil, amiodarone, aprepitant, astemizole, buspirone, cisapride, cocaine, conivaptan, cortisol, cyclosporine, dapsone, darunavir, dasatinib, diazepam, dihydroergotamine, dihydropyridines, diltiazem, erythromycin, ethinyl estradiol, everolimus, felodipine, fluticasone, gestodene, indinavir, lidocaine, lopinavir, lovastatin, macrolides, maraviroc, methadone, miconazole, midazolam, mifepristone, nifedipine, nisoldipine, paclitaxel progesterone, quetiapine, quinidine, rapamycin, ritonavir, saquinavir, sildenafil, simvastatin, sirolimus, spironolactone, sulfamethoxazole, sufentanil, tacrolimus, tamoxifen, terfenadine, testosterone, tetrahydrocannabinol, tolvaptan, tipranavir, triazolam, troleandomycin, vardenafil, verapamil Avasimibe, barbiturates, carbamazepine, glucocorticoids, pioglitazone, phenytoin, rifampin, St. John's wort Amprenavir, azamulin, boceprevir, clarithromycin, conivaptan, diltiazem, erythromycin, fluconazole, grapefruit juice (furanocoumarins), indinavir, itraconazole, ketoconazole, lopinavir, mibefradil, nefazodone, nelfinavir, posaconazole, ritonavir, saquinavir, telaprevir, telithromycin, troleandomycin, verapamil, voriconazole

Reproduced, with permission, from AJ, Katzung BG, Trevor AJ: Basic & Clinical Pharmacology. 13th ed. New York: McGraw-Hill Education; 2013.

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