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Chapter 39: Orthomyxoviruses (Influenza Viruses)

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Which of the following statements regarding the prevention and treatment of influenza is correct?

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(A) Booster doses of vaccine are not recommended.

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(B) Drugs that inhibit neuraminidase are active only against influenza A.

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(C) As with some other live vaccines, the attenuated influenza vaccine should not be given to pregnant women.

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(D) The influenza vaccine contains several serotypes of virus.

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(E) The virus strains in the influenza vaccine do not vary from year to year.

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Which of the following statements about the neuraminidase of influenza virus is not correct?

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(A) Is embedded in the outer surface of the viral envelope

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(B) Forms a spike structure composed of four identical monomers, each with enzyme activity

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(C) Facilitates release of virus particles from infected cells

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(D) Lowers the viscosity of the mucous film in the respiratory tract

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(E) Is antigenically similar among all mammalian influenza viruses

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Which of the following statements reflects the pathogenesis of influenza?

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(A) The virus enters the host in airborne droplets.

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(B) Viremia is common.

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(C) The virus frequently establishes persistent infections in the lung.

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(D) Pneumonia is not associated with secondary bacterial infections.

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(E) Viral infection does not kill cells in the respiratory tract.

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Which of the following symptoms is not typical of influenza?

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(A) Fever

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(B) Muscular aches

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(C) Malaise

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(D) Dry cough

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(E) Rash

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The type-specific antigen (A, B, or C) of influenza viruses is found on which viral constituent?

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(A) Hemagglutinin

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(B) Neuraminidase

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(C) Nucleocapsid

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(D) Polymerase complex

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(E) Major nonstructural protein

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(F) Lipid in the viral envelope

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A 70-year-old nursing home patient refused the influenza vaccine and subsequently developed ...

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