TABLE A6–3: Recommended Interventions for Prevention of Contrast Nephrotoxicity
|Intervention ||Recommendation ||Recommendation Gradea |
|Contrast || |
Minimize contrast volume/dose
Use noniodinated contrast studies
Use low- or iso-osmolar contrast agents
|Medications || ||A-2 |
|Isotonic sodium chloride (0.9%) || |
Initiate infusion 3–12 hours prior to contrast exposure and continue 6–24 hours postexposure
Infuse at 1–1.5 mL/kg/h adjusting postexposure as needed to maintain a urine flow rate of 150 mL/h
Alternatively, in urgent cases, initiate infusion at 3 mL/kg/h, beginning 1 hour prior to contrast exposure, then continue at 1 mL/kg/h for 6 hours postexposure
|N-acetylcysteine || ||B-1 |
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