TY  - CHAP
M1  - Book, Section
TI  - Skin and Soft-Tissue Infections
A1  - Wells, Barbara G.
A1  - DiPiro, Joseph T.
A1  - Schwinghammer, Terry L.
A1  - DiPiro, Cecily V.
PY  - 2017
T2  - Pharmacotherapy Quick Guide
AB  - Bacterial  infections  of  the  skin  can  be  classified  as  primary  or  secondary  (Table  47–1).  Primary  bacterial  infections  are  usually  caused  by  a  single  bacterial  species  and  involve  areas  of  generally  healthy  skin  (eg,  impetigo  and  erysipelas).  Secondary  infections,  however,  develop  in  areas  of  previously  damaged  skin  and  are  frequently  polymicrobic.The  conditions  that  may  predispose  a  patient  to  the  development  of  skin  and  soft-tissue  infections  (SSTIs)  include  (1)  a  high  concentration  of  bacteria;  (2)  excessive  moisture  of  the  skin;  (3)  inadequate  blood  supply;  (4)  availability  of  bacterial  nutrients;  and  (5)  damage  to  the  corneal  layer,  allowing  for  bacterial  penetration.The  majority  of  SSTIs  are  caused  by  gram-positive  organisms  and,  less  commonly,  gram-negative  bacteria  present  on  the  skin  surface.  Staphylococcus  aureus  and  Streptococcus  pyogenes  account  for  the  majority  of  SSTIs.  Community-associated  methicillin-resistant  S.  aureus  (CA-MRSA)  has  emerged  and  is  often  isolated  in  otherwise  healthy  patients.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1144735323
ER  -