TY  - CHAP
M1  - Book, Section
TI  - Chapter 7. Drug Transporters
A1  - Tsunoda, Shirley M.
A1  - Bednarczyk, Dallas
A1  - Okochi, Hideaki
A2  - Bertino, Joseph S.
A2  - DeVane, C. Lindsay
A2  - Fuhr, Uwe
A2  - Kashuba, Angela D.
A2  - Ma, Joseph D.
PY  - 2013
T2  - Pharmacogenomics: An Introduction and Clinical Perspective
AB  - Discuss  the  roles  that  membrane  transporters  play  in  drug  disposition  and  action.Explain  how  drug  transporters  influence  drug  action  in  the  intestine,  liver,  kidney,  and  blood–brain  barrier.Describe  how  pharmacogenetic  changes  in  P-glycoprotein  may  affect  drug  concentrations  and  pharmacodynamics.Provide  examples  of  how  pharmacogenetic  variants  may  affect  pharmacokinetics  of  substrate  compounds  for  the  following  transporters:  breast  cancer  resistance  protein  (BCRP),  organic  anion-transporting  polypeptide  1B1  (OATP1B1),  bile  salt  export  pump  (BSEP),  organic  cation  transporter  1  (OCT1),  organic  cation  transporter  2  (OCT2),  and  multidrug  and  toxin  extrusion  1  (MATE1).  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/24
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=56876077
ER  -