TY  - CHAP
M1  - Book, Section
TI  - Physiologic Drug Distribution and Protein Binding
A1  - Sun, He
A1  - Zhao, Hong
A2  - Shargel, Leon
A2  - Yu, Andrew B.C.
Y1  - 2016
N1  - 
T2  - Applied Biopharmaceutics & Pharmacokinetics, 7e
AB  - Describe  the  physiology  of  drug  distribution  in  the  body.Explain  how  drug  distribution  is  affected  by  blood  flow,  protein,  and  tissue  binding.Describe  how  drug  distribution  can  affect  the  apparent  volume  of  distribution.Explain  how  volume  of  distribution,  drug  clearance,  and  half-life  can  be  affected  by  protein  binding.Determine  drug–protein  binding  constants  using  in  vitro  methods.Evaluate  the  impact  of  change  in  drug–protein  binding  or  displacement  on  free  drug  concentration.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1117898970
ER  -