TY  - CHAP
M1  - Book, Section
TI  - Ionic Equilibria and Buffers
A1  - Sandmann, Beverly J.
A1  - Dash, Alekha K.
A1  - Al-Achi, Antoine
A1  - Greenwood, Robert
A2  - Mobley, W. Cary
A2  - Amiji, Mansoor M.
A2  - Cook, Thomas J.
Y1  - 2019
N1  - 
T2  - Applied Physical Pharmacy, 3e
AB  - Learning  ObjectivesAfter  completing  this  chapter,  the  reader  should  be  able  to:Define  a  strong  electrolyte,  a  weak  electrolyte,  and  a  nonelectrolyte.Differentiate  between  a  cation  and  an  anion.Define  an  acid,  a  base,  and  the  different  types  of  salts.Recognize  and  give  examples  of  pharmaceutically  important  acids,  bases,  and  salts.Describe  the  ionization  equilibria  of  strong  and  weak  electrolytes.Calculate  and  interpret  the  ionization  constants  of  weak  acids  and  bases  (Ka,  Kb,  pKa,  and  pKb).Calculate  the  pH  and  pOH  and  the  concentrations  of  the  components  of  aqueous  solutions  of  weak  electrolytes.Calculate  the  pH  and  pOH  of  mixtures  of  weak  acids  and  bases,  diprotic  acids,  and  ampholyte  solutions.Calculate  the  percent  ionization  of  weak  electrolytes  as  a  function  of  pH.Describe  the  physiologic  implications  of  percentage  of  ionization  of  weak  electrolytes  in  the  absorption,  transport,  and  excretion  of  drugs  (pH  partition  hypothesis).Define  a  buffer  solution  and  list  its  components.Calculate  the  pH  of  a  buffer  solution.Define  and  calculate  the  buffer  capacity  of  a  buffer  solution.Calculate  the  quantity  of  ingredients  needed  to  prepare  a  buffer  solution.Recognize  the  various  types  of  buffer  solutions  and  their  methods  of  preparation.Define  ionic  strength  and  understand  its  effect  on  ionization.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=1163540237
ER  -