TY  - CHAP
M1  - Book, Section
TI  - Chapter 8. Pulmonary Arterial Hypertension (PAH)
A1  - Attridge, Rebecca L.
A1  - Moote, Rebecca
A1  - Levine, Deborah J.
A2  - Attridge, Rebecca L.
A2  - Miller, Monica L.
A2  - Moote, Rebecca
A2  - Ryan, Laurajo
PY  - 2013
T2  - Internal Medicine: A Guide to Clinical Therapeutics
AB  - Clinical  pathological  definition:  vasculopathy  of  the  small  pulmonary  arteries  which  leads  to  ↑  pulmonary  vascular  resistance;  may  progress  to  right  heart  dysfunction  &  failureHemodynamic  definition:  mean  pulmonary  artery  pressure  (mPAP)  ≥25mmHg  at  rest,  AND  pulmonary  capillary  wedge  pressure  (PCWP)  or  left  ventricular  end-diastolic  pressure  (LVEDP)  ≤15mmHg  measured  by  right  heart  catheterizationEstablished  disease  mediators:  endothelin-1,  prostacyclin,  nitric  oxide  (J  Am  Cardiol  2009;53:1573)  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/20
UR  - accesspharmacy.mhmedical.com/content.aspx?aid=57286808
ER  -