RT Book, Section
A1 Ding, Hong
A2 Shargel, Leon
A2 Yu, Andrew B.C.
SR Print(0)
ID 1117901135
T1 Modified-Release Drug Products and Drug Devices
T2 Applied Biopharmaceutics & Pharmacokinetics, 7e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071830935
LK accesspharmacy.mhmedical.com/content.aspx?aid=1117901135
RD 2024/04/20
AB Define  modified-release  drug  products.Differentiate  between  conventional,  immediate-release,  extended-release,  delayed-release,  and  targeted  drug  products.Explain  the  advantages  and  disadvantages  of  extended-release  drug  products.Describe  the  kinetics  of  extended-release  drug  products  compared  to  immediate-release  drug  products.Explain  when  an  extended-release  drug  product  should  contain  an  immediate-release  drug  dose.Explain  why  extended-release  beads  in  capsule  formulation  may  have  a  different  bioavailability  profile  compared  to  an  extended-release  tablet  formulation  of  the  same  drug.Describe  several  approaches  for  the  formulation  of  an  oral  extended-release  drug  product.Explain  why  a  transdermal  drug  product  (patch)  may  be  considered  an  extended-release  drug  product.Describe  the  components  of  a  transdermal  drug  delivery  system.Explain  why  an  extended-release  formulation  of  a  drug  may  have  a  different  efficacy  profile  compared  to  the  same  dose  of  drug  given  in  as  a  conventional,  immediate-release,  oral  dosage  form  in  multiple  doses.List  the  studies  that  might  be  required  for  the  development  of  an  extended-release  drug  product.List  the  several  achievements  on  the  drug  devices  based  on  the  modified-release  drug  design.