RT Book, Section
A1 Dienstag, Jules L.
A2 Jameson, J. Larry
A2 Fauci, Anthony S.
A2 Kasper, Dennis L.
A2 Hauser, Stephen L.
A2 Longo, Dan L.
A2 Loscalzo, Joseph
SR Print(0)
ID 1159156110
T1 Acute Viral Hepatitis
T2 Harrison's Principles of Internal Medicine, 20e
YR 2018
FD 2018
PB McGraw-Hill Education
PP New York, NY
SN 9781259644016
LK accesspharmacy.mhmedical.com/content.aspx?aid=1159156110
RD 2024/04/20
AB Acute  viral  hepatitis  is  a  systemic  infection  affecting  the  liver  predominantly.  Almost  all  cases  of  acute  viral  hepatitis  are  caused  by  one  of  five  viral  agents:  hepatitis  A  virus  (HAV),  hepatitis  B  virus  (HBV),  hepatitis  C  virus  (HCV),  the  HBV-associated  delta  agent  or  hepatitis  D  virus  (HDV),  and  hepatitis  E  virus  (HEV).  All  these  human  hepatitis  viruses  are  RNA  viruses,  except  for  hepatitis  B,  which  is  a  DNA  virus  but  replicates  like  a  retrovirus.  Although  these  agents  can  be  distinguished  by  their  molecular  and  antigenic  properties,  all  types  of  viral  hepatitis  produce  clinically  similar  illnesses.  These  range  from  asymptomatic  and  inapparent  to  fulminant  and  fatal  acute  infections  common  to  all  types,  on  the  one  hand,  and  from  subclinical  persistent  infections  to  rapidly  progressive  chronic  liver  disease  with  cirrhosis  and  even  hepatocellular  carcinoma,  common  to  the  bloodborne  types  (HBV,  HCV,  and  HDV),  on  the  other.