RT Book, Section A1 Stringer, Janet L. SR Print(0) ID 1142820502 T1 Absorption, Distribution, and Clearance T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 5e YR 2017 FD 2017 PB McGraw-Hill Education PP New York, NY SN 9781259861079 LK accesspharmacy.mhmedical.com/content.aspx?aid=1142820502 RD 2024/04/19 AB The liver is a metabolic machine and often inactivates drugs on their way from the GI tract to the body. This is called the first-pass effect.