RT Book, Section
A1 Stringer, Janet L.
SR Print(0)
ID 1142821069
T1 Drugs Used in Dementia
T2 Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 5e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259861079
LK accesspharmacy.mhmedical.com/content.aspx?aid=1142821069
RD 2024/04/23
AB Dementia,  including  Alzheimer  disease,  has  been  found  to  involve  a  number  of  systems  in  the  brain.  There  is  evidence  for  a  decrease  in  markers  of  cholinergic  neuron  activity  and  for  changes  in  brain  glutamate,  dopamine,  norepinephrine,  serotonin,  and  somatostatin.  Eventually,  cholinergic  neurons  die  or  are  destroyed.  Treatment  has  focused  on  increasing  the  amount  of  acetylcholine  in  the  synapse  by  inhibiting  the  breakdown  of  acetylcholine.