RT Book, Section A1 Rosselli, Jennifer A2 Sutton, S. Scott SR Print(0) ID 1158313560 T1 Peripheral Arterial Disease T2 McGraw-Hill's NAPLEX® Review Guide, 3e YR 2019 FD 2019 PB McGraw-Hill Education PP New York, NY SN 9781260135923 LK accesspharmacy.mhmedical.com/content.aspx?aid=1158313560 RD 2024/04/23 AB Peripheral arterial disease (PAD) encompasses noncardiac systemic atherosclerosis. PAD most commonly manifests in arteries of the lower extremities and may also be present in the carotid, mesenteric, renal, brachiocephalic, and subclavian vasculature. The incidence of PAD increases with age beginning at 40 years. Additional factors identified by the Framingham Heart Study to increase the risk for developing PAD include diabetes, hypercholesterolemia, cigarette smoking, and hypertension (Table 8-1). Patients with PAD have a fourfold increase in coronary artery disease and death compared to individuals without PAD.