RT Book, Section
A1 McCain, Keith R.
A1 Foster, Howell R.
A2 Sutton, S. Scott
SR Print(0)
ID 7256454
T1 Chapter 66. Clinical Toxicology
T2 McGraw-Hill's NAPLEX® Review Guide
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-175562-7
LK accesspharmacy.mhmedical.com/content.aspx?aid=7256454
RD 2024/04/19
AB Clinical  toxicology  involves  the  assessment  and  management  of  disease  caused  by  exposure  to  an  agent(s)  in  which  adverse  effects  may  develop.  All  natural  and  synthetic  xenobiotics  are  capable  of  causing  toxicity  in  humans.  It  is  paramount  to  recognize  that  all  substances  can  be  poisonous  in  a  specific  situation.  Paracelsus,  the  father  of  modern  toxicology,  identified  this  principle  in  stating  that  "solely  the  dose  determines  that  a  thing  is  not  a  poison.“1  As  such,  some  agents  are  capable  of  severe  consequence  at  microgram  dose  (botulinum  toxin)  while  others  are  typically  viewed  as  harmless,  but  at  extremes  can  be  lethal  (water  intoxication).2