RT Book, Section A1 Trevor, Anthony J. A1 Katzung, Bertram G. A1 Kruidering-Hall, Marieke M. A1 Masters, Susan B. SR Print(0) ID 56985336 T1 Chapter 59. Drugs Used in Gastrointestinal Disorders T2 Katzung & Trevor's Pharmacology: Examination & Board Review, 10e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-178923-3 LK accesspharmacy.mhmedical.com/content.aspx?aid=56985336 RD 2024/04/20 AB Table Graphic Jump Location|Download (.pdf)|PrintAcid-peptic diseaseA group of disorders involving erosion or ulceration of the mucosal lining of the gastrointestinal tract; includes GERD, gastric and duodenal ulcers, nonulcer dyspepsia, and stress-related gastritisAntiemeticA drug that reduces nausea and vomitingGastroesophageal reflux disease (GERD)Esophageal irritation or inflammation due to reflux of stomach acid; also known as heartburnGastroparesisParalysis of the muscles of the stomach and possibly other parts of the gastrointestinal tract due to damage to gastrointestinal nerves or muscle; common in advanced diabetes and advanced Parkinson diseaseInflammatory bowel disease (IBD)Inflammatory disorder involving irritation and ulceration of the colon and rectum (ulcerative colitis) or the colon plus more proximal parts of the gastrointestinal tract (Crohn's disease)Irritable bowel syndrome (IBS)Disease of unknown origin characterized by episodes of abdominal discomfort and abnormal bowel function (diarrhea, constipation, or both)ProkineticA drug that promotes gastrointestinal motilityProton pumpThe parietal cell H+/K+ ATPase that uses the energy of ATP to secrete protons into the stomach (Figure 59–1); final common target of drugs that suppress acid secretion