RT Book, Section
A1 Scullion, Bridget Fowler
A1 Ryan, Laurajo
A2 Attridge, Rebecca L.
A2 Miller, Monica L.
A2 Moote, Rebecca
A2 Ryan, Laurajo
SR Print(0)
ID 57295616
T1 Chapter 45. Pain Management
T2 Internal Medicine: A Guide to Clinical Therapeutics
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-174580-2
LK accesspharmacy.mhmedical.com/content.aspx?aid=57295616
RD 2024/04/20
AB Pain  is  a  warning  mechanism;  tissue  damage  causes  release  of  prostaglandins  &  other  substances  that  send  signals  via  peripheral  nerves  (nociceptors)  to  dorsal  horn  of  spinal  cord;  from  spinal  cord,  neurotransmitters  transmit  pain  signals  to  spinothalamic  tract  &  thalamus  which  process  the  pain  signal  in  the  brain;  neurotransmitters  (NE,  5HT)  &  endogenous  opioids  in  brain  &  spinal  cord  modulate  pain  signal