RT Book, Section A1 Pelletier-Dattu, Catherine E. SR Print(0) ID 1114498337 T1 Antimicrobial Medications T2 Lange Smart Charts: Pharmacology, 2e YR 2017 FD 2017 PB McGraw-Hill Medical PP New York, NY SN 9780071774369 LK accesspharmacy.mhmedical.com/content.aspx?aid=1114498337 RD 2024/04/18 AB Table Graphic Jump Location|Download (.pdf)|PrintBlackwater FeverSyndrome of hemolytic anemia, hemoglobinuria, and renal failure associated with massive parasitemia.CinchonismPoisoning syndrome associated with quinine, quinidine, and Cinchona; symptoms include tinnitus, deafness, headache, blurry vision, and nausea.Disulfiram ReactionSyndrome that occurs due to coingestion of alcohol and disulfiram; disulfiram blocks aldehyde dehydrogenase, leading to accumulation of acetaldehyde; symptoms include nausea, headache, flushing, and hypotension.G6PD DeficiencyLack of enzyme important in the oxidation/reduction capabilities of the red blood cell; deficiency leads to hydrogen peroxide accumulation, which causes hemolysis. Hemolysis often associated with drugs that produce oxidative stress (eg, sulfonamides).Gray Baby SyndromeMay be caused by deficiency of a hepatic enzyme required for the degradation of chloramphenicol or impaired renal function; syndrome is characterized by circulatory collapse, cyanosis (gray color), acidosis, abdominal distention, coma, and death.Lassa FeverA hemorrhage febrile illness associated with arenavirus infection.Mazzotti ReactionSyndrome of fever, urticaria, tender lymphadenopathy, arthralgias, abdominal pain, edema, hypotension, and tachycardia seen with treatment of microfilariasis with Ivermectin, Praziquantel, and Albendazole.MethemoglobinemiaAccumulation of methemoglobin, which is a form of hemoglobin with a low oxygen affinity. Methemoglobinemia results in pseudocyanosis, tissue hypoxia, and death.Stevens-Johnson SyndromeImmunologic reaction characterized by lesions of the skin and mucous membranes; involves both the mouth and eyes.SuperinfectionA novel infection in addition to a pre-existing one.TrachomaChronic inflammation of the conjunctiva caused by Chlamydia trachomatis.