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Courses in Therapeutics and Disease State Management | Infectious Disease I:

03. Antimicrobial Prophylaxis in Surgery

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Michael W. Perry
  • Differentiate between prophylactic, presumptive, and therapeutic antibiotics in the perioperative patient.
  • Identify patient-specific risk factors for surgical site infections (SSIs).
  • Identify procedure-specific risk factors for SSIs.
  • List common pathogens responsible for SSIs.
  • Explain the importance of timing of antimicrobial prophylaxis for surgery.
  • Choose an evidence-based prophylactic antimicrobial regimen for specific types of surgeries.
  • Individualize prophylactic antimicrobial regimens by considering the type of surgery, intrinsic patient risk factors, and knowledge of common pathogenic organisms.
  • Recommend an alternative prophylactic antimicrobial regimen for patients with life-threatening allergies to first-line therapies.
  • Identify clinical scenarios where multiple dose regimens of prophylactic antimicrobials are appropriate as compared to single dose regimens.
  • List nonpharmacological interventions effective at reducing the risk of postoperative SSIs.


External Activity
Lecture and Study Notes for Antimicrobial Prophylaxis in Surgery Supplemental File: Infectious Disease I - 03(2). Antimicrobial Prophylaxis in Surgery (Courses in Therapeutics and Disease State Management)(2).pptx
AccessPharmacy > Pharmacotherapy: A Pathophysiologic Approach, 9e > Chapter 101. Antimicrobial Prophylaxis in Surgery
Standalone Test
External Activity
Clinical practice guidelines for antimicrobial prophylaxis in surgery. Am J Health Syst Pharm


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