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Courses in Therapeutics and Disease State Management | Infectious Disease I:

14. Severe Sepsis and Septic Shock

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AUTHORS:
Michael W. Perry
LEARNING OBJECTIVES:
  • Define the following terms: systemic inflammatory response syndrome, sepsis, severe sepsis, and septic shock
  • Describe the typical clinical presentation including signs, symptoms, hemodynamic measure, and laboratory tests for each condition above
  • Describe the microbial pathogens of severe sepsis
  • Describe the mechanism of sepsis, including the components involving inflammatory cytokines and other mediators and the coagulation system
  • Describe the early goal-directed therapy of sepsis
  • Describe the significance of prompt initiation of broad-spectrum antibiotics
  • Determine appropriate fluid resuscitation for sepsis with colloids or crystalloids
  • Recommend an appropriate antibiotic regimen for treatment of sepsis based on patient characteristics and primary site of infection
  • Determine the role of vasoactive agents in supporting the physiologic function of a patient with sepsis, and select the appropriate vasoactive agents based on the details of a patient’s condition
  • Explain the benefits of glycemic control in patients with sepsis
  • Recommend the appropriate use of corticosteroids in severe sepsis and septic shock
  • Describe an appropriate monitoring program for patients with sepsis
External Activity
Lecture and Study Notes for Severe Sepsis and Septic Shock Supplemental File: Infectious Disease I - 14(1). Severe Sepsis and Septic Shock (Courses in Therapeutics and Disease State Management)(1).pptx
Note
Required
Chapter
AccessPharmacy > Pharmacotherapy: A Pathophysiologic Approach, 10e > Sepsis and Septic Shock
Required
Standalone Test
Severe Sepsis and Septic Shock Quiz(Passing Score )
Required
External Activity
Management of Sepsis and Septic Shock
Note
Optional
External Activity
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
Note
Optional
External Activity
A users’ guide to the 2016 surviving sepsis guidelines
Note
Optional

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