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VIDEO 236-7: T2* images of the heart (left panel) and the liver (right panel) of a patient who has hemochromatosis.

From: Harrison's Principles of Internal Medicine, 20e

Note that iron and the liver are markedly darkened in these movies, indicating high load of iron in the heart muscle and liver. The rate of signal reduction (decay) in the myocardium and liver can be calculated as T2* value expressed in milliseconds. In this case, the T2* was at 10 ms. T2* <20 ms in patients with cardiomyopathy has been shown to indicate iron toxicity as the etiology of the cardiomyopathy, and it carries prognostic valve for such patients at risk of cardiac iron toxicity.

10 secs
Author(s) Marcelo F. Di Carli, Raymond Y. Kwong, Scott D. Solomon
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