Which of the following agents would NOT be appropriate to use to treat simple nausea/vomiting?
Promethazine
Hydroxyzine
Meclizine
Droperidol
Trimethobenzamide
Droperidol is a butyrophenone and is used in palliative care and PONV. Even in these instances, it is not recommended as first-line therapy and has the possibility of some cardiac adverse effects including QT prolongation. Hydroxyzine, meclizine, and trimethobenzamide have antihistamine-anticholinergic action and are indicated for simple N/V. Promethazine is a phenothiazine and is appropriate to use for simple N/V.