Which of the following statements regarding PPIs is true?
It is preferable to take a PPI immediately after a meal.
The patient should expect to feel relief of symptoms within 15 to 30 minutes of taking the PPI.
Long-term PPI therapy has been associated with increased risk of bone fractures and vitamin B12 deficiency.
PPIs can cause hyperglycemia, and blood glucose needs to be more frequently monitored in diabetes patients using PPI therapy.
Long-term PPIs therapy has been associated with an increased risk of bone fractures, hypomagnesemia, and vitamin B12 deficiency. PPIs are most effective when they are taken 30 to 60 minutes prior to the start of a meal, usually breakfast. It takes about 2 to 3 hours after PPI administration for a patient to experience relief of symptoms. PPIs do not alter blood glucose levels.