Readers of previous editions of Goldfrank's Toxicologic Emergencies are undoubtedly aware that the editors have always felt that an emphasis on general management of patients who are poisoned or overdosed coupled with sound medical management is as important as the selection and use of a specific antidote in the vast majority of cases. Nevertheless, there are some instances when nothing other than the timely use of a specific antidote is an essential lifesaving intervention. For this reason, and also because the use of such strategies may be problematic, controversial, or unfamiliar to the practitioner as new therapeutic approaches continue to emerge and old standards are reevaluated, we have included a section (or sections) at the end of each chapter where an in-depth discussion of such material is relevant.