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Carbamazepine is an iminostilbene derivative related to the tricyclic antidepressants that is used in the treatment of tonic-clonic (grand mal), partial, or secondarily generalized seizures (Table 11-1).1,2,3, and 4 Although methods have been suggested to treat acute seizures with carbamazepine, lack of an intravenous dosage form has limited its use in this area. Thus, the drug is used primarily as a prophylactic agent in the chronic therapy of epilepsy. Carbamazepine is also a useful agent to treat trigeminal neuralgia and bipolar affective disorders.7,8, and 9

TABLE 11-1International Classification of Epileptic Seizures With Recommended Therapies

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