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Chapter 17. Toxic Responses of the Ocular and Visual System

In which of the following locations would one NOT find melanin?

a. iris.

b. ciliary body.

c. retinal pigment epithelium (RPE).

d. uveal tract.

e. sclera.

Systemic exposure to drugs and chemicals is most likely to target which of the following retinal sites?

a. RPE and ganglion cell layer.

b. optic nerve and inner plexiform layer.

c. RPE and photoreceptors.

d. photoreceptors and ganglion cell layer.

e. inner plexiform layer and RPE.

Which of the following structures is NOT part of the ocular fundus?

a. retina.

b. lens.

c. choroid.

d. sclera.

e. optic nerve.

Drugs and chemicals in systemic blood have better access to which of the following sites because of the presence of loose endothelial junctions at that location?

a. retinal choroid.

b. inner retina.

c. optic nerve.

d. iris.

e. ciliary body.

All of the following statements regarding ocular irritancy and toxicity are true EXCEPT:

a. The Draize test involves instillation of a potentially toxic liquid or solid into the eye.

b. The effect of the irritant in the Draize test is scored on a weighted scale for the cornea, iris, and conjunctiva.

c. The Draize test usually uses one eye for testing and the other as a control.

d. The Draize test has strong predictive value in humans.

e. The cornea is evaluated for opacity and area of involvement in the Draize test.

Which of the following statements regarding color vision deficits is FALSE?

a. Inheritance of a blue–yellow color deficit is common.

b. Bilateral deficits in the visual cortex can lead to color blindness.

c. Disorders of the outer retina produce blue–yellow deficits.

d. Drug and chemical exposure most commonly ...

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