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Chapter 39: Orthomyxoviruses (Influenza Viruses)

Which of the following statements regarding the prevention and treatment of influenza is correct?

(A) Booster doses of vaccine are not recommended.

(B) Drugs that inhibit neuraminidase are active only against influenza A.

(C) As with some other live vaccines, the attenuated influenza vaccine should not be given to pregnant women.

(D) The influenza vaccine contains several serotypes of virus.

(E) The virus strains in the influenza vaccine do not vary from year to year.

Which of the following statements about the neuraminidase of influenza virus is not correct?

(A) Is embedded in the outer surface of the viral envelope

(B) Forms a spike structure composed of four identical monomers, each with enzyme activity

(C) Facilitates release of virus particles from infected cells

(D) Lowers the viscosity of the mucous film in the respiratory tract

(E) Is antigenically similar among all mammalian influenza viruses

Which of the following statements reflects the pathogenesis of influenza?

(A) The virus enters the host in airborne droplets.

(B) Viremia is common.

(C) The virus frequently establishes persistent infections in the lung.

(D) Pneumonia is not associated with secondary bacterial infections.

(E) Viral infection does not kill cells in the respiratory tract.

Which of the following symptoms is not typical of influenza?

(A) Fever

(B) Muscular aches

(C) Malaise

(D) Dry cough

(E) Rash

The type-specific antigen (A, B, or C) of influenza viruses is found on which viral constituent?

(A) Hemagglutinin

(B) Neuraminidase

(C) Nucleocapsid

(D) Polymerase complex

(E) Major nonstructural protein

(F) Lipid in the viral envelope

A 70-year-old nursing home patient refused the influenza vaccine and subsequently developed ...

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