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This chapter will be most useful after having a basic understanding of the material in Chapter 55, Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents in Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 12th Edition. In addition to the material presented here Chapter 55 contains:
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Understand the mechanisms of action and resistance of tetracyclines, macrolides, vancomycin, linezolid, daptomycin, and quinupristin/dalfopristin
Describe the unique toxicities of antibiotics that are inhibitors of bacterial protein synthesis
Describe the uses and untoward reactions of vancomycin
Identify the drug–drug interactions that occur with some of these antibiotics
Understand how linezolid, daptomycin, and quinupristin/dalfopristin are used to treat methicillin-resistant and vancomycin-resistant organisms
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DRUGS INCLUDED IN THIS CHAPTER
Azithromycin (ZITHROMAX)
Bacitracin
Chloramphenicol
Clarithromycin (BIAXIN, others)
Clindamycin (CLEOCIN PHOSPHATE, others)
Daptomycin (CUBICIN)
Doxycycline
Erythromycin
Linezolid (ZYVOX)
Mupirocin (BACTROBAN)
Polymyxin
Quinupristin/dalfopristin (SYNERCID)
Spectinomycin
Teicoplanin
Telithromycin (KETEX)
Tetracycline
Tigecycline
Vancomycin (VANCOCIN)
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