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Section 3: Respiratory Disorders

The aerosol particle size most likely to deposit in the lower airways is:

A. 10-20 μm

B. 5-10 μm

C. 1-5 μm

D. 0.1-0.5 μm

The answer is C.

Advantages of spacer devices include all of the following except:

A. Enhanced lung delivery

B. Decreased oropharyngeal deposition of drug

C. Increased percent of drug particles achieving respirable droplet size

D. Standardization of spacers to make them substitutable

The answer is D.

An objective assessment used to monitor response to therapy in an acute severe asthma exacerbation include which one of the following:

A. Functional exhaled nitric oxide (FeNO)

B. Impulse Oscillometry

C. Serum cortisol levels

D. Pulse oximetry

The answer is D.

Pharmacologic responses to β2-agonists include all of the following except:

A. Increased neuromuscular transmission

B. Smooth muscle relaxation

C. Stimulate uterine contractions

D. Vasodilation of the vasculature

The answer is C.

A predominant risk factor for children to have continued asthma is:

A. Atopy

B. Birth weight in the 95% percentile

C. Early exposure to cats or dogs

D. Family history of medication allergy

E. Rural environment

The answer is A.

Which one of the following statements is CORRECT about the major characteristics of marketed dry powder inhalers (DPIs) used to deliver drugs to the lungs?

A. Drug delivery is breath-actuated, requiring minimal hand-lung coordination by the patient.

B. DPI's have been standardized to require the same inspiratory flow rate.

C. Only inhaled corticosteroids are available as a DPI.

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