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Section 3: Respiratory Disorders

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The aerosol particle size most likely to deposit in the lower airways is:

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A. 10-20 μm

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B. 5-10 μm

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C. 1-5 μm

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D. 0.1-0.5 μm

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The answer is C.

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Advantages of spacer devices include all of the following except:

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A. Enhanced lung delivery

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B. Decreased oropharyngeal deposition of drug

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C. Increased percent of drug particles achieving respirable droplet size

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D. Standardization of spacers to make them substitutable

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The answer is D.

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An objective assessment used to monitor response to therapy in an acute severe asthma exacerbation include which one of the following:

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A. Functional exhaled nitric oxide (FeNO)

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B. Impulse Oscillometry

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C. Serum cortisol levels

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D. Pulse oximetry

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The answer is D.

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Pharmacologic responses to β2-agonists include all of the following except:

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A. Increased neuromuscular transmission

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B. Smooth muscle relaxation

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C. Stimulate uterine contractions

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D. Vasodilation of the vasculature

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The answer is C.

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A predominant risk factor for children to have continued asthma is:

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A. Atopy

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B. Birth weight in the 95% percentile

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C. Early exposure to cats or dogs

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D. Family history of medication allergy

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E. Rural environment

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The answer is A.

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Which one of the following statements is CORRECT about the major characteristics of marketed dry powder inhalers (DPIs) used to deliver drugs to the lungs?

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A. Drug delivery is breath-actuated, requiring minimal hand-lung coordination by the patient.

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B. DPI's have been standardized to require the same inspiratory flow rate.

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C. Only inhaled corticosteroids are available as a DPI.

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