Section 16: Oncologic Disorders
Which of the following steps are not parts of the multistage process of carcinogenesis?
A new genetic alteration is identified in an individual patient's resected tumor. The normal gene product appears to inhibit inappropriate cellular growth and proliferation. Which of the following terms adequately classifies the gene?
A 62-year-old postmenopausal woman with newly diagnosed breast cancer has a 1 cm tumor mass in her left breast. Additional diagnostic tests show the cancer has not spread to the lymph nodes or distant sites. What is the stage of disease for this patient?
A 65-year-old man is recently diagnosed with locally advanced colon cancer. The cancer has spread to regional lymph nodes, but not distant sites. The patient undergoes major surgery to remove the tumor. Following surgery, the patient will receive combination chemotherapy. Which of the following best describes the treatment?
The patient will receive oxaliplatin, fluorouracil, and leucovorin. Leucovorin is included in the chemotherapy regimen to:
A. reduce fluorouracil toxicity
B. increase fluorouracil cytotoxicity
C. reduce oxaliplatin toxicity
D. increase oxaliplatin cytotoxicity
An average risk 55-year-old premenopausal woman with no smoking history should not be counseled regarding the following procedures as part of routine cancer screening?
A. pap with HPV DNA test, every 5 years