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Chapter 90. Lung Cancer

All of the following scenarios are consistent with a recommendation to be screened with a low-dose CT scan for lung cancer (according to the recent guidelines)?

A. A 45-year-old man who has smoked a pack a day since the age of 13 years

B. A 65-year-old woman with a 40 pack–year smoking history, who quit smoking 10 years ago

C. A 50-year-old coal miner whose father and brother died of lung cancer in their 60s

D. All of the above fit the screening criteria

E. None of the above fit the screening criteria

Treatment options for a patient with stage IIIb adenocarcinoma and an ECOG PS score of 3 may include all of the following EXCEPT:

A. Palliative radiotherapy

B. Surgical resection of a distant metastasis

C. Platinum-containing doublet chemotherapy

D. Single agent targeted agent

E. Treatment of comorbidities to improve performance

A well-performing stage IV adenocarcinoma NSCLC patient with a mutation in exon 19 of the EGFR gene should be treated with:

A. Cetuximab

B. Cisplatin-gemcitabine

C. Afatinib

D. Bevacizumab

E. Radiotherapy

Premedications to prevent nausea and vomiting with cisplatin vinorelbine should include:

A. A neurokinin inhibitor

B. Metoclopramide

C. Promethazine

D. A benzodiazepine

E. Diphenhydramine

Which of the following is NOT considered to be an acceptable regimen for advanced stage squamous cell NSCLC?

A. Carboplatin/paclitaxel

B. Cisplatin/vinorelbine

C. Gemcitabine/paclitaxel

D. Pemetrexed/cisplatin

E. Gemcitabine/docetaxel

Which of the following is a reasonable premedication for an EGFR-targeted therapy?

A. Dexamethasone

B. Doxycycline

C. Fosaprepitant

D. Folate and ...

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