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Chapter 97. Malignant Lymphomas

Which of the following kinase inhibitors can be used in the treatment of patients with follicular lymphoma that has progressed despite multiple chemotherapy treatments?

A. Regorafenib

B. Vandetanib

C. Imatinib

D. Idelalisib

E. Dasatinib

Which of the following unique toxicities are associated with the ABVD regimen?

A. Pulmonary fibrosis

B. Hemorrhagic cystitis

C. Hepatic encephalopathy

D. Osteopenia

E. All of the above

For a patient presenting with lymphadenopathy and a suspected diagnosis of lymphoma, the most appropriate diagnostic test would be:

A. Abdominal x-ray

B. Fine-needle aspirate

C. Surgical lymph node excision

D. Bone scan

E. Serum protein electrophoresis

Which of the following prophylactic medications should be administered before the infusion of single-agent rituximab?

A. Diphenhydramine

B. Filgrastim

C. Ondansetron

D. Allopurinol

E. Fosaprepitant

Which of the following agents should not be administered intrathecally for a patient with primary CNS lymphoma?

A. Cytarabine

B. Vincristine

C. Methotrexate

D. Hydrocorotisone

E. All of these medications can be administered intrathecally

Which of the following is not a negative prognostic factor in advanced Hodgkin lymphoma?

A. Platelets < 100,000/μL (100 × 109/L)

B. WBCs > 15,000/mm3(15 × 109/L)

C. Stage IV disease

D. Male gender

E. Albumin < 4 g/dL (40 g/L)

Standard chemotherapy for front-line treatment for advanced (stage III/IV) diffuse large B-cell lymphoma is:

A. m-BACOD

B. PROMACE-CytaBOM

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