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2.3.3: Review, dispense, and administer drugs and drug products, considering physical attributes of drug products

Select the cephalosporin that may be used in the treatment of acute otitis media that has a bitter tasting suspension and has differing bioavailability rates depending upon the oral formulation used.

(A) Ceftin

(B) Vantin

(C) Zithromax

(D) Cleocin

The correct answer is (A).

Cefuroxime axetil (Ceftin) is available in tablets and suspension formulations. The tablet and suspensions are not interchangeable because of differing bioavailability rates. Cefuroxime suspension is gritty and bitter tasting. Cefuroxime is also available as an injection, but the parenteral formulation is seldom used.

Answer (B) is incorrect. Cefpodoxime (Vantin) has a bitter tasting suspension, but the tablets and suspension have similar bioavailability rates.

Answer (C) is incorrect. Azithromycin (Zithromax) is available as a suspension, tablet and injection; however, the formulations have similar bioavailability rates and the suspension is not bitter tasting.

Answer (D) is incorrect. Clindamycin (Cleocin) has a poor tasting oral liquid, but the capsules and liquid are interchangeable.

Select the cephalosporin that may be used in the treatment of acute otitis media that has a bitter tasting suspension and has differing bioavailability rates depending upon the oral formulation used.

(A) Ceftin

(B) Vantin

(C) Zithromax

(D) Cleocin

The correct answer is (A).

Cefuroxime axetil (Ceftin) is available in tablets and suspension formulations. The tablet and suspensions are not interchangeable because of differing bioavailability rates. Cefuroxime suspension is gritty and bitter tasting. Cefuroxime is also available as an injection, but the parenteral formulation is seldom used.

Answer (B) is incorrect. Cefpodoxime (Vantin) has a bitter tasting suspension, but the tablets and suspension have similar bioavailability rates.

Answer (C) is incorrect. Azithromycin (Zithromax) is available as a suspension, tablet and injection; however, the formulations have similar bioavailability rates and the suspension is not bitter tasting.

Answer (D) is incorrect. Clindamycin (Cleocin) has a poor tasting oral liquid, but the capsules and liquid are interchangeable.

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