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2.3.4: Review, dispense, and administer drugs and drug products, considering specific instructions and techniques for administration

How often is one NuvaRing inserted vaginally?

(A) every 3 days

(B) every 21 days

(C) every 7 days

(D) every 14 days

The Correct Answer is: B

One vaginal contraceptive ring should be inserted for 3 weeks, or 21 days (B).

A vaginal contraceptive ring should be inserted for 3 weeks, not for 3 days (A), 7 days (C), or 14 days (D).

Topic: Contraception

Which contraceptive agent is formulated as an injection?

(A) Demulen

(B) Mirena

(C) Estrostep

(D) Depo-Provera

The Correct Answer is: D

Depo-Provera (D) is an injectable, progestin-only contraceptive available intramuscularly and subcutaneously.

Demulen (A) is an oral combined contraceptive. Mirena (B) is an intrauterine system that provides progestin daily. Estrostep (C) is an oral combined contraceptive.

Topic: Contraception

Which of the following medications for HCV is administered subcutaneously three times per week?

(A) Interferon alfacon-1

(B) Peg-interferon alpha-1a

(C) Peg-interferon alpha-2b

(D) Ribavirin

The Correct Answer is: A

Interferon alfacon-1 (A) is administered subcutaneously three times per week.

The pegylation process increases the drug's half-life and allows for the interferon to be administered weekly (B and C). Ribavirin (D) is administered orally twice a day.

Topic: Hepatitis

Which of the following agents is dosed weekly?

(A) Methotrexate

(B) Leflunomide

(C) Hydroxychloroquine

(D) Sulfasalazine

The Correct Answer is: A

Methotrexate (A) is dosed on a weekly basis and is available orally and for intramuscular, subcutaneous, and intravenous injection. Weekly dosing of the drug appears to cause less gastrointestinal toxicity (less damage to the mucosa) and fewer side effects than daily dosing. It is important to be vigilant when reviewing methotrexate prescriptions to verify proper dosing frequency. Emphasize to your patients that this medication is taken on a weekly, not daily, basis to minimize the risk of overdose.

Leflunomide (B) is dosed daily or twice daily. Hydroxychloroquine (C) is dosed daily. Sulfasalazine (D) is dosed bid or tid.

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