Skip to Main Content
Home Books Harper's Illustrated Biochemistry, 31e

Section XI: Special Topics (C)

  • Sections
  • Print
  • Get Citation

    Citation

    AMA Citation
    Special Topics (C). In: Rodwell VW, Bender DA, Botham KM, Kennelly PJ, Weil P. Rodwell V.W., Bender D.A., Botham K.M., Kennelly P.J., Weil P Eds. Victor W. Rodwell, et al.eds. Harper's Illustrated Biochemistry, 31e New York, NY: McGraw-Hill; . http://accesspharmacy.mhmedical.com/content.aspx?bookid=2408&sectionid=188837146. Accessed February 19, 2019.
    MLA Citation
    . "Special Topics (C)." Harper's Illustrated Biochemistry, 31e Rodwell VW, Bender DA, Botham KM, Kennelly PJ, Weil P. Rodwell V.W., Bender D.A., Botham K.M., Kennelly P.J., Weil P Eds. Victor W. Rodwell, et al. New York, NY: McGraw-Hill, , http://accesspharmacy.mhmedical.com/content.aspx?bookid=2408&sectionid=188837146.

    Download citation file:

    RIS (Zotero)
    EndNote
    BibTex
    Medlars
    ProCite
    RefWorks
    Reference Manager
    Mendeley
    © Copyright
  • Tools
  • Search Book
  • Clip
Top

Section XI – Special Topics (C)

Which one of the following statements regarding the blood coagulation pathways is NOT CORRECT?

A. The components of the extrinsic Xase (tenase) complex are factor VIIa, tissue factor, Ca2+, and factor X.

B. The components of the intrinsic Xase (tenase) complex are factors IXa and VIIIa, Ca2+, and factor X.

C. The components of the prothrombinase complex are factors Xa and Va, Ca2+, and factor II (prothrombin).

D. The extrinsic and intrinsic Xase complexes and prothrombinase complex require anionic procoagulant phosphatidylserine on low-density lipoprotein (LDL) for their assembly.

E. Fibrin formed by cleavage of fibrinogen by thrombin is covalently cross-linked by the action of factor XIIIa, which itself is formed by the action of thrombin on factor XIII.

On which one of the following coagulation factors does a patient taking warfarin for his thrombotic disorder have decreased Gla (γ-carboxyglutamate) residues?

A. Tissue factor

B. Factor XI

C. Factor V

D. Factor II (prothrombin)

E. Fibrinogen

Of the listed proteins, only factor II is a vitamin K-dependent coagulation factor.

A 65-year-old man suffers a myocardial infarction and is given tissue plasminogen activator within 6 hours of onset of the thrombosis to achieve which one of the following?

A. Prevent activation of the extrinsic pathway of coagulation

B. Inhibit thrombin

C. Enhance degradation of factors VIIIa and Va

D. Enhance fibrinolysis

E. Inhibit platelet aggregation

Which one of the following statements regarding platelet activation in hemostasis and thrombosis is NOT CORRECT?

A. Platelets adhere directly to subendothelial collagen via GPIa-IIa and GPVI, while binding of GPIb-IX-V is mediated via von Willebrand factor.

B. The aggregating agent thromboxane A2 is formed from arachidonic acid liberated from platelet membrane phospholipids by the action of phospholipase A2.

C. The aggregating agent ADP is released from the dense granules of activated platelets.

D. The aggregating agent thrombin activates intracellular phospholipase Cβ, which forms the internal effector molecules 1,2-diacylglycerol and 1,4,5-inositol ...

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.

This site uses cookies to provide, maintain and improve your experience. MHE Privacy Center Close