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Chapter 3. Immunity, Infection, & Inflammation

Cells responsible for innate immunity are activated most commonly by

A. glucocorticoids

B. pollen

C. carbohydrate sequences in bacterial cell walls

D. eosinophils

E. thrombopoietin

A biotechnology company is working to design a new therapeutic strategy for cancer that involves triggering an enhanced immune response to cellular proteins that are mutated in the disease. Which of the following immune cells or processes will most likely not be required for a successful therapy?

A. Cytotoxic T cells

B. Antigen presentation in the context of MHC-II

C. Proteosomal degradation

D. Gene rearrangements producing T cell receptors

E. The immune synapse

A six-year-old boy is brought to the pediatrician with complaints of progressive excessive thirst, increased urination, weight loss, and severe fatigue. A glucose tolerance test results in a diagnosis of type 1 diabetes mellitus and the patient is treated effectively with injected insulin. The emergent symptoms in this patient reflect a failure of which immune process?

A. Antibody synthesis

B. Neutrophil chemotaxis

C. Antigen presentation

D. Tolerance

E. Complement activation

A 20-year-old college student comes to the student health center in April complaining of runny nose and congestion, itchy eyes, and wheezing. She reports that similar symptoms have occurred at the same time each year, and that she obtains some relief from over-the-counter antihistamine drugs, although they make her too drowsy to study. Her symptoms can most likely be attributed to inappropriate synthesis of which of the following antibodies specific for tree pollen?

A. IgA

B. IgD

C. IgE

D. IgG

E. IgM

The ability of the blood to phagocytose pathogens and mount a respiratory burst is increased by

A. interleukin-2 (IL-2)

B. granulocyte colony-stimulating factor (G-CSF)

C. erythropoietin

D. interleukin-4 (IL-4)

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