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Chapter 28. Transport & Metabolic Functions of the Liver

Which of the following cell types protects against sepsis secondary to translocation of intestinal bacteria?

A. Hepatic stellate cell

B. Cholangiocyte

C. Kupffer cell

D. Hepatocyte

E. Gallbladder epithelial cell

A 60-year-old man comes to his physician complaining of a progressive increase in his girth despite attempts to diet. He is also jaundiced and complains of nausea and malaise. When a large needle is inserted into his abdomen, several liters of tan fluid drain out. An increase in which of the following is not involved in this fluid accumulation?

A. Portal pressure

B. Hepatic collagen

C. Plasma albumin

D. Stellate cell activity

E. Plasma transudation

P450s (CYPs) are highly expressed in hepatocytes. In which of the following do they not play an important role?

A. Bile acid formation

B. Carcinogenesis

C. Steroid hormone formation

D. Detoxification of drugs

E. Glycogen synthesis

A surgeon is studying new methods of liver transplantation. She performs a complete hepatectomy in an experimental animal. Before the donor liver is grafted, a rise in the blood level of which of the following would be expected?

A. Glucose

B. Fibrinogen

C. 25-Hydroxycholecalciferol

D. Conjugated bilirubin

E. Estrogens

A scientist studying the function of the different cell types in the liver creates a mouse in which the activity of one specific cell type is transiently ablated. The mice exhibit behavioral defects consistent with encephalopathy. The function of which of the following cell types was most likely targeted?

A. Hepatic stellate cell

B. Cholangiocyte

C. Kupffer cell

D. Hepatocyte

E. Gallbladder epithelial cell

A patient suffering from severe ulcerative colitis undergoes a total colectomy with formation of ...

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