Source: Fish DN. Skin and soft-tissue infections. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 10th ed. New York, NY: McGraw-Hill; 2017. http://accesspharmacy.mhmedical.com/content.aspx?bookid=1861§ionid=146071658. Accessed July 21, 2017.
Infections common in infants, young children, elderly, and patients with nephrotic syndrome.
Commonly occurs in areas of preexisting lymphatic obstruction or edema.
Flu-like symptoms (fever and malaise) prior to appearance of lesions.
Infected area painful, often described as burning pain.
Lesions bright red and edematous, with lymphatic streaking.
Mild temperature elevation.
MEANS OF CONFIRMATION AND DIAGNOSIS
TREATMENT: PHARMACOLOGIC THERAPY
TABLE 1.Evidence-Based Recommendations for Treatment of Skin and Soft-Tissue Infections |Favorite Table|Download (.pdf) TABLE 1. Evidence-Based Recommendations for Treatment of Skin and Soft-Tissue Infections
|Recommendations ||Recommendation Grade |
|Erysipelas || |
|Most infections caused by S. pyogenes. Penicillin (oral or IV depending on clinical severity) drug of choice ||A-I |
|If Staphylococcus aureus suspected, penicillinase-resistant penicillin or first-generation cephalosporin should be used. ||A-I |