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Source: Fish DN. Skin and soft-tissue infections. In: DiPiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach. 10th ed. New York, NY: McGraw-Hill; 2017. http://accesspharmacy.mhmedical.com/content.aspx?bookid=1861§ionid=146071658. Accessed March 23, 2017.
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CLINICAL PRESENTATION
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MEANS OF CONFIRMATION AND DIAGNOSIS
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DIFFERENTIAL DIAGNOSIS
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Relief of symptoms and discomfort.
Improve cosmetic appearance of lesions.
Rapid eradication of infection.
Prevent further spread of infection.
Prevent formation of new lesions.
Prevent complications such as cellulitis.
Prevent recurrence.
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TREATMENT: NONPHARMACOLOGIC THERAPY
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TREATMENT: PHARMACOLOGIC THERAPY
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Penicillinase-resistant penicillins (eg, dicloxacillin) are agents of first choice because of increased isolation of S. aureus (Tables 1 and 2).
First line therapy for mild impetigo not involving multiple lesions or the face: topical mupirocin or retapamulin ointment for 5 days.
Treat for 7 days.
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