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Instructors can request access to the Casebook Instructor's Guide on AccessPharmacy. Email User Services ( for more information.


After completing this case study, the reader should be able to:

  • Recognize the clinical manifestations of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) secondary to BPH.

  • Differentiate between obstructive and irritative symptoms in patients with BPH.

  • Recommend appropriate pharmacotherapeutic treatment for BPH.

  • Identify and manage drug interactions associated with BPH pharmacotherapy.

  • Recognize when surgical therapies should be considered for patients with BPH.

  • Understand how some drugs can exacerbate BPH symptoms.


Chief Complaint

“I’m up four to five times a night feeling that I have to urinate, and then when I get to the bathroom all I do is dribble. I’m very lightheaded when I stand up, and sometimes I don’t make it to the bathroom in time. I have a girlfriend now, but I am finding it difficult to be intimate with her. Also, going to the bathroom all night is really impacting my love life.”


Jimmy McCracken is a 65-year-old man with a long-standing history of UTIs. He has a history of urosepsis requiring hospitalization. He is being evaluated because of complaints of worsening urinary hesitancy, nocturia, and dribbling. He also has a new complaint of ED. He would like information on prescription medications to treat his urinary symptoms but is not opposed to using natural products.



Laminectomy 10 years ago


Chronic UTIs

Type 2 DM



Osteoarthritis (new onset)

Cat allergy (new onset)


Educated through the 12th grade. Father died of massive MI at age 78; mother died of natural causes at age 91.


Worked for 35 years in a grocery store; retired 7 years ago. Married once. Wife deceased 6 months ago (stroke); one daughter, two granddaughters. Lives alone but is starting to become more socially active. He recently joined a senior dating website and has started dating a 60-year-old woman. He also just adopted a 3-year-old cat from the humane society. Although he reports being allergic to cat dander, he feels that she has added happiness back in to his life and uses medications to keep his allergies under control because he doesn’t want to give up the cat. Used smokeless tobacco × 35 years (quit 10 years ago); heavy ETOH in the past, occasional glass of wine now.


In conversation, he is alert, friendly, and courteous. He has no c/o ...

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