Instructors can request access to the Casebook Instructor's Guide on AccessPharmacy. Email User Services (email@example.com) for more information.
After completing this case study, the reader should be able to:
Recognize the clinical manifestations of spontaneous bacterial peritonitis (SBP; also known as primary bacterial peritonitis).
List the goals of antimicrobial therapy for SBP.
Recommend appropriate therapy for SBP.
Monitor therapy for SBP for safety and efficacy.
Recommend secondary prophylaxis for SBP.
“My belly hurts so bad I can barely move.”
John Chavez is a 47-year-old Hispanic man who was brought to the ED by his wife. She stated that he has been suffering from nausea, vomiting, and severe abdominal pain for the past 2–3 days. His intake of food and fluids has been minimal over the past several days.
Cirrhosis, diagnosed last year with onset of ascites
Cholecystectomy 15 years ago
Mother was alcoholic; died 10 years ago in car accident. Father’s history unknown.
Retired construction worker; EtOH abuse with 10–12 cans of beer per day × 25 years and occasional heavier use on weekends; denies use of tobacco or illicit drugs; inconsistent adherence to medications; per patient’s wife he avoids salt but confirms he eats fast food two to three times per week
Furosemide 40 mg PO once daily
Acetaminophen 325 mg PO PRN for pain
As noted in the HPI. Denies any hematemesis or melena.
Thin man who appears older than his stated age, with a distended abdomen and in severe pain
BP 154/82, P 102, RR 32, T 38.2°C; current Wt 92 kg, (IBW 68 kg)
Jaundiced, warm, coarse, and very dry. Spider angiomata present on chest, back and arms.
Yellow sclera; PERRLA; Oropharynges show poor dentition but are otherwise unremarkable.
Supple; normal-size thyroid; no JVD or palpable lymph nodes
Lungs are CTA; shallow and frequent breathing
Tachycardia, normal S1 and S2 with no S3 or S4