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Questions
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What are the risk factors for developing endometrial cancer?
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A. Obesity is the correct answer because of the increase estrogen exposure due to peripheral conversion of estrone to estradiol.
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B. Progesterone use is actually protective of uterine lining.
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C. HPV is not associated with development of endometrial cancer.
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D. has not been closely associated with development with endometrial cancer.
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What is included in the screening recommendations for endometrial cancer?
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D. Transvaginal ultrasound
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C. While there is no standard screening recommendations annual pelvic exam would be most beneficial in early detection of endometrial cancer.
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A. HPV testing and B. PAP smear are beneficial for screening for cervical cancer not endometrial cancer.
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D. The use of transvaginal ultrasound is not used for routine screening tool for any of the gynecologic malignancies rather it is used as a diagnostic tool.
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Which of following would be included in the primary treatment of stage III endometrial cancer?
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C. Surgery + chemotherapy
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D. Surgery + chemotherapy + radiation
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D. Surgery, chemotherapy + radiation would be standard treatment for advanced endometrial cancer that has demonstrate significant improvement on progression free and overall survival.
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A. Surgery alone is primary treatment for stage I.
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B. Surgery + radiation for early stage II endometrial cancer.
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C. Surgery palliative intent for improvement of symptoms + chemotherapy would perhaps be used in those patients that had stage IV endometrial cancer.
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Based on the KEYNOTE study which of the following would be indicated for treatment of MSI-High endometrial cancer?
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B. Pembrolizumab would be correct based on the KEYNOTE study that demonstrated MSI-high endometrial cancer was more likely to respond to PDL-1 inhibitor ...