Goldfrank's Toxicologic Emergencies
is a multi-authored text of
close to 2000 pages prepared by using the education and management
principles we apply at the New York City Poison Center and at our clinical
sites. In this ninth edition of Goldfrank's Toxicologic Emergencies,
we proudly offer readers an approach to medical toxicology using
evidence-based principles viewed through a lens of bedside clinical
practice. The case history is no longer incorporated in the chapter, but
these cases and the critical questions appropriate for discussion are
available on the website initially established in the eighth edition. We
believe that this supplementary use of the cases recreates a learning
environment much like the original text published in 1976 and permits us to
use additional text space without creating a heavier, less portable text. In
this edition, all the chapters have been revised, and several new chapters
have been added. The greatest additions are found in the form of both
Antidotes in Depth and Special Considerations, which allow us to address
major advances in thought in a highly focused fashion.
Our goal is to assist in understanding new intellectual
approaches with an emphasis on the ever-expanding role of medical and
clinical toxicologists at the beginning of the twenty-first century. We have
continued to increase the number of nationally and internationally known
authors who have expertise in their respective areas by reassigning many of
the chapters to these experts.
The ninth edition
expands on our progress in the eighth edition to use the electronic format.
The book has been dramatically improved with the use of full-color graphics
and a single art style that will expand and enhance the educational value of
the imagery of each chapter and of the image section on the website.
The complete "text" now consists of a hard copy
component that offers readers the option of holding while consulting, as
they have done previously, as well as an electronic workbook component
available on our website (goldfrankstoxicology.com
The workbook, which includes both case studies and
annotated multiple-choice questions, is now available on this website and is
dramatically enhanced. Many of the cases are relevant classic examples of
toxicologic emergencies, and the remainder are new, extensively discussed
cases from our regional monthly meetings at the New York City Poison Center.
The collective wisdom of many of the current and former text authors
continues to guide these sessions as it has for 30 years. Drs. Lewis S.
Nelson and Robert S. Hoffman have analyzed these problems, distilled the
discussions, and recreated the spirit of these meetings in the printed
versions of the cases. Revised annotated multiple-choice questions based on
each chapter were developed by the respective chapter authors and edited by
Drs. Howard A. Greller and Dean G. Olsen to enhance self-learning and meet
the intellectual needs of our readers. Each question has been meticulously
meta-tagged by these editors. This allows the learner to sort by a variety
of test strategies that are focused on a particular xenobiotic, clinical
finding, or therapeutic strategy, to name a few, with the goal of improved
The rewriting and
reorganization of this edition of the text has again required an enormous
personal effort by each author and the editors as it has in the past, which
we hope will facilitate reading, learning, and better patient care. Work on
the next edition of this text literally begins the day that the current
edition is published because this is such a rapidly evolving field. Although
"tearing down" and reconstructing the text between each edition is an
extreme exercise, it prevents the editors from accepting and promulgating
unfounded treatments and outdated concepts. We hope that you agree that this
exercise is worthwhile and that each "new text" continues to serve you well.
As always, we encourage your thoughtful comments, and we will do our best,
as always, to incorporate your suggestions into future editions.
If this text helps to provide better patient care and
stimulates interest in medical toxicology for students of medicine, nursing,
and pharmacy and by residents, fellows, and faculty in diverse specialties,
our efforts will have indeed been worthwhile.Lewis
S. NelsonNeal A. LewinMary Ann HowlandRobert
S. HoffmanLewis R. GoldfrankNeal E. Flomenbaum