Upon completion of the chapter, the reader will be able to:
- 1. Describe the impact of stroke on the general population of the United States (incidence and outcomes).
- 2. Identify the known risk factors for stroke in a patient with either an ischemic or a hemorrhagic stroke.
- 3. Determine which risk factors are modifiable in a given stroke patient and develop a strategy for risk reduction.
- 4. Given a patient presentation differentiate cardioembolic stroke from other causes of ischemic stroke.
- 5. Explain the pathophysiologic mechanism underlying the development of acute ischemic stroke.
- 6. List the major arteries supplying blood to the brain and their approximate location.
- 7. Compare and contrast transient ischemic attack (TIA) and acute ischemic stroke.
- 8. Propose a plan for the diagnostic workup of a patient with presumed ischemic stroke.
- 9. Discuss the relative merits of anticoagulation with unfractionated heparin in the management of acute ischemic stroke.
- 10. Given a patient case, select an appropriate antiplatelet regimen for the prevention of secondary ischemic stroke.
- 11. Develop monitoring plans for patients receiving aspirin, clopidogrel, and dipyridamole + aspirin for the prevention of ischemic stroke.
- 12. Assess a patientâs eligibility to receive intravenous thrombolytic therapy, given a diagnosis of acute ischemic stroke.
- 13. Plan a treatment strategy for using intravenous thrombolytic therapy in acute ischemic stroke, including an individual monitoring plan.
- 14. Determine whether a stroke patient is a candidate for carotid endarterectomy (CEA) for stroke prevention.
- 15. Compare the cost-effectiveness of the various prevention and treatment strategies used in patients with a history of stroke
Stroke is the leading cause of disability among adults and the third leading cause of death in the United States, behind cardiovascular disease and all cancers. Despite a 30% reduction in stroke mortality between 1995 and 2005, stroke occurs in the United States at a rate of almost 800,000 per year and results in 150,000 deaths.1 Aggressive efforts to organize stroke care at the local ...