Upon completion of the chapter, the reader will be able to:
- 1. Describe the epidemiology, etiology, and prognosis of acute pancreatitis.
- 2. Identify medications with possible, probable, or definite associations with acute pancreatitis.
- 3. Discuss the usual course of acute pancreatitis and strategies for predicting severity of illness.
- 4. Discuss the role of fluid replacement in the treatment of acute pancreatitis.
- 5. Recommend appropriate nutritional support for patients with acute pancreatitis.
- 6. Compare the place in therapy for various opioid analgesics used in the treatment of acute pancreatitis.
- 7. Interpret the literature on the use of prophylactic antibiotics in acute pancreatitis.
- 8. Differentiate between the different pathophysiologic mechanisms involved in the development of chronic pancreatitis.
- 9. Assess a patient for chronic pancreatitis based on presenting signs and symptoms, lab values, and diagnostic studies.
- 10. Recommend appropriate nonpharmacologic therapy for patients with chronic pancreatitis.
- 11. Design individualized pharmacotherapeutic regimens for treating the pain associated with chronic pancreatitis.
- 12. Justify the use of pancreatic enzyme supplements for the treatment of malabsorption associated with chronic pancreatitis.
- 13. Discuss the advantages and disadvantages of the various dosage forms of the currently available pancreatic enzyme supplements.
- 14. Justify the use of adjunctive antisecretory agents in the treatment of patients with chronic pancreatitis.
- 15. Design an evaluation and monitoring plan for patients receiving therapy for chronic pancreatitis.
Pancreatitis is inflammation of the pancreas with variable involvement of regional tissues or remote organ systems.1 Acute pancreatitis is characterized by severe pain in the upper abdomen and elevations of pancreatic enzymes in the blood.1–3 In the majority of patients, acute pancreatitis is a mild, self-limiting disease ...