Source: Law RM, Law DTS.
Dermatologic Drug Reactions and Common Skin Conditions. In: DiPiro
JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Posey LM, eds. Pharmacotherapy: A Pathophysiologic Approach.
8th ed. http://accesspharmacy.com/content.aspx?aid=7998475.
Accessed May 27, 2012.
- Acute, inflammatory contact dermatitis of buttocks, genitalia,
perineal regions, lower abdomen, or thigh folds of infant or toddler
resulting from direct fecal and moisture contact with skin in occlusive
- Erythematous rash; vesicles and oozing erosions may be
present in severe cases.
- May be infected by Candida species
and present with confluent red plaques, papules, and pustules.
- Based on clinical presentation.
- Relieve symptoms.
- Remove precipitating factors.
- Prevent recurrences.
- Avoid adverse treatment effects.
- Improve quality of life.
- Frequent diaper changes
- Air drying (remove diaper for as long as practical)
- Gentle cleansing with nonsoap cleansers and lukewarm water
- May apply zinc oxide for astringent and absorbent properties
and to provide effective moisture barrier.
- Apply topical imidazole antifungal agents for Candida (yeast).
Discontinue therapy when rash subsides and continue barrier product.
- May use very low potency topical corticosteroid
(hydrocortisone 0.5–1%) for short periods (1–2 weeks)
in severe inflammatory cases.
- Educate caregivers on causative factors, preventive measures,
and useful treatments.
- Evaluate patients periodically to assess efficacy of therapy
and possible side effects.