TY - CHAP M1 - Book, Section TI - Application of Pharmacokinetics to Clinical Situations A1 - Tam, Vincent H. A2 - Shargel, Leon A2 - Yu, Andrew B.C. PY - 2016 T2 - Applied Biopharmaceutics & Pharmacokinetics, 7e AB - Define Medication Therapy Management (MTM) and explain how MTM can improve the success of drug therapy.Explain what “critical-dose drugs” are and name an example.Define therapeutic drug monitoring and explain which drugs should be monitored through a therapeutic drug monitoring service.Calculate a drug dosage regimen in an individual patient for optimal drug therapy for a drug that has complete pharmacokinetic information and for a drug that has incomplete pharmacokinetic information.Explain the relationship of changing the dose and/or the dosing interval on the , , and C.Define drug–drug interactions and the mechanisms of drug–drug interactions, and provide examples.Provide instructions to a patient who has missed a dose and discuss the therapeutic implications.Explain how the pharmacokinetics of a drug may be altered in special populations, such as the elderly, infants, obese patients, and patients with renal or hepatic disease.Explain how Bayesian theory can help determine the probability of a diagnostic test to give accurate results.Define population pharmacokinetics and explain how population pharmacokinetics enables the estimate of pharmacokinetic parameters from relatively sparse data obtained from study subjects. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1117902047 ER -