TY - CHAP M1 - Book, Section TI - Carbohydrates: Fructose Metabolism and Feeding Behaviors A1 - King, Michael W. PY - 2014 T2 - Integrative Medical Biochemistry Examination and Board Review AB - High-Yield TermsHigh-fructose corn syrup (HFCS): refers to the sugar syrup generated from corn starch by enzymatic conversion of a portion of the glucose to fructose. Commonly contains 55% fructose and identified as HFCS-55HFCS and sucrose: represent the 2 primary sources of fructose in the human dietGLUT5 and GLUT2: intestinal sugar transporters responsible for fructose uptake and then delivery to the blood, respectivelyKetohexokinase: two isoforms KHK-A and KHK-C catalyze phosphorylation of fructose to fructose 1-phosphate, also called frucktokinaseAldolase B: enzyme catalyzing hydrolysis of fructose 1-phosphate to glyceraldehyde and dihydroxyacetone phosphate (DHAP)Fructose-induced feeding: metabolism of fructose within the brain results in suppression of anorexigenic signals while activating orexigenic signalsHereditary fructose intolerance: potentially fatal infant disorder resulting from defect in the level of aldolase B activity SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesspharmacy.mhmedical.com/content.aspx?aid=1122103430 ER -